Cutaneous periumbilical purpura in disseminated strongyloidiasis in cancer patients: a pathognomonic feature of potentially lethal disease?

نویسندگان

  • Jorge I F Salluh
  • Fernando A Bozza
  • Tatiana S Pinto
  • Luisa Toscano
  • Peter F Weller
  • Marcio Soares
چکیده

Cutaneous manifestations in disseminated strongyloidiasis are infrequent but should raise the suspicion for its diagnosis. We retrospectively evaluated the charts of six patients with cancer and a proven diagnosis of disseminated strongyloidiasis. All patients had received prophylaxis with albendazole before starting antineoplastic therapy, which included high-dose steroids. They presented with septic shock, acute respiratory failure and characteristic purpuric periumbilical skin lesions. Strongyloides larvae were identified in tracheal aspirates (n=5), gastric aspirates (n=4), lung (n=2) and skin biopsies (n=2). All patients died despite antihelminthic therapy and intensive care support.

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عنوان ژورنال:
  • The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

دوره 9 5  شماره 

صفحات  -

تاریخ انتشار 2005